SequelSEC

Upstream Bio, Inc. UPB

Pharmaceutical Preparations · CIK 0002022626 · Fiscal year ends 1231

Revenue
$3.16M
Fiscal year ended 2026-06-30
Operating income
-$169.98M
Fiscal year ended 2026-06-30
Free cash flow
Unavailable
Fiscal year ended 2026-06-30

Upstream Bio, Inc. (UPB) reported revenue of $3.16M and net income of -$156.50M for the fiscal year ended 2026-06-30. This page shows 1 annual period of income statement, balance sheet and cash flow figures normalized from Upstream Bio, Inc.’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Pharmaceutical Preparations.

Income

Upstream Bio, Inc. income by fiscal year, in US dollars, normalized from SEC filings.
Metric2026-06-30
Revenue$3.16M
Cost of revenueUnavailable
Gross profitUnavailable
Operating income-$169.98M
Net income-$156.50M
Research & development$145.80M
Weighted-average diluted sharesUnavailable
Pretax incomeUnavailable
Income tax expense$0
Diluted EPSUnavailable
Selling, general & administrativeUnavailable
General & administrative$27.34M
Selling & marketingUnavailable

Balance

Upstream Bio, Inc. balance by fiscal year, in US dollars, normalized from SEC filings.
Metric2026-06-30
Cash & equivalents$79.40M
Total assets$281.17M
Current assets$279.60M
Total liabilities$10.21M
Current liabilities$9.99M
Total equity incl. NCI$270.96M
Temporary (mezzanine) equityUnavailable
InventoryUnavailable
Accounts receivable$772.00K
GoodwillUnavailable
Long-term debtUnavailable
Accounts payable$2.31M

Cash flow

Upstream Bio, Inc. cash flow by fiscal year, in US dollars, normalized from SEC filings.
Metric2026-06-30
Operating cash flow-$136.34M
Capital expendituresUnavailable
Investing cash flow$165.29M
Financing cash flow$4.99M
Net change in cash$33.94M
Stock-based compensation$14.10M
Common dividends paidUnavailable
Common share repurchasesUnavailable
Depreciation & amortization$202.00K

Derived

Upstream Bio, Inc. derived by fiscal year, in US dollars, normalized from SEC filings.
Metric2026-06-30
Free cash flowUnavailable
Gross marginUnavailable
Operating margin-5382.6%
FCF marginUnavailable
SBC / revenue446.5%
Current ratio27.99x
Revenue YoY growth16.0%
Net margin-4955.7%
R&D / revenue4616.8%
CapEx / revenueUnavailable
Long-term debt / equityUnavailable
Effective tax rateUnavailable

Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open UPB in the interactive workspace to inspect any figure back to its filing.

Source filings

10-Q · Filed 2026-08-11View SEC filing
10-Q · Filed 2026-05-13View SEC filing
10-K · Filed 2026-03-26View SEC filing
10-Q · Filed 2025-11-05View SEC filing
10-Q · Filed 2025-08-06View SEC filing
10-Q · Filed 2025-05-06View SEC filing

Companies in the same industry

Every accounting identity this site checks — the balance sheet, the gross profit bridge and the cash flow statement — reconciles in every period shown.