SequelSEC

RHYTHM PHARMACEUTICALS, INC. RYTM

Pharmaceutical Preparations · CIK 0001649904 · Fiscal year ends 1231

Revenue
$189.76M
Fiscal year ended 2025-12-31
Operating income
-$192.02M
Fiscal year ended 2025-12-31
Free cash flow
-$116.63M
Fiscal year ended 2025-12-31

Valuation, from the filing

Public float$3.80BMarket value of stock held by non-affiliates, as stated on the cover page for 2025-06-30
Float per share$55.65Float divided by shares outstanding in the same filing. A floor under the share price on that date, not the price itself.
Float / revenue20.0×A lower bound on the multiple, because affiliate holdings are excluded.
Float / equity27.3×A lower bound on the multiple, because affiliate holdings are excluded.

Every figure here is drawn from the 10-K cover page and the statements behind it, so each one traces to a filing. Public float counts only stock held by non-affiliates, which makes these floors rather than estimates: a high multiple is conclusive, a low one may mean cheap or may mean closely held. The float was measured on 2025-06-30, not today, and each multiple below it uses the figures for the fiscal year ending 2025-12-31 — the year that filing covered.

How this compares in its industry

Percentile among the Pharmaceutical Preparations filers on this site, highest value first. A high percentile means a large figure, which is good for a margin and not for leverage — the ranking says where the company sits, not whether that is where it should be.

MeasureReportedPercentile
Gross margin89.7%85th
Revenue YoY growth45.8%74th
CapEx / revenue0.5%30th
Long-term debt / equity0.73x60th
R&D / revenue88.2%40th
Operating margin-101.2%58th
SBC / revenue35.2%57th
Current ratio4.41x56th
Net margin-103.6%54th
FCF margin-61.5%52th

RHYTHM PHARMACEUTICALS, INC. (RYTM) reported revenue of $189.76M and net income of -$196.54M for the fiscal year ended 2025-12-31. This page shows 10 annual periods of income statement, balance sheet and cash flow figures normalized from RHYTHM PHARMACEUTICALS, INC.’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Pharmaceutical Preparations.

Income

RHYTHM PHARMACEUTICALS, INC. income by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Revenue$189.76M$130.13M$77.43M$23.64M$3.15M$0$0$0$0$0
Cost of revenue$19.49M$13.37M$9.30M$2.13M$599.00KUnavailableUnavailableUnavailableUnavailableUnavailable
Gross profit$170.26M$116.76M$68.13M$21.50M$2.56MUnavailableUnavailableUnavailableUnavailableUnavailable
Operating income-$192.02M-$265.50M-$184.36M-$179.16M-$170.06M-$136.58M-$146.00M-$78.42M-$32.41M-$25.90M
Net income-$196.54M-$260.60M-$184.68M-$181.12M-$69.61M-$134.00M-$140.73M-$74.06M-$33.71MUnavailable
Research & development$167.34M$237.96M$134.95M$108.63M$104.13M$90.45M$109.45M$50.34M$22.89M$19.59M
Weighted-average diluted sharesshares 64.98Mshares 61.00Mshares 57.67Mshares 52.12Mshares 49.60Mshares 44.13Mshares 36.42MUnavailableUnavailableUnavailable
Pretax income-$196.04M-$260.26M-$184.11M-$181.12M-$69.61MUnavailableUnavailableUnavailableUnavailableUnavailable
Income tax expense$497.00K$346.00K$564.00KUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Diluted EPS$-3.11$-4.34$-3.20$-3.47$-1.40$-3.04$-3.86UnavailableUnavailableUnavailable
Selling, general & administrative$194.94M$144.30M$117.53M$92.03M$68.49M$46.12M$36.55M$28.08M$9.52M$6.31M
General & administrativeUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Selling & marketingUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable

Balance

RHYTHM PHARMACEUTICALS, INC. balance by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Cash & equivalents$54.30M$89.14M$60.08M$127.68M$59.25M$100.85M$62.29M$49.54M$34.24M$6.54M
Total assets$480.20M$392.27M$332.74M$382.48M$329.52M$187.07M$308.52M$260.21M$151.74M$12.34M
Current assets$466.92M$374.20M$308.27M$354.24M$308.39M$181.67M$302.40M$258.69M$150.67M$11.18M
Total liabilities$210.17M$227.72M$162.99M$118.22M$45.37M$20.54M$27.50M$13.95M$6.95M$5.04M
Current liabilities$105.94M$115.52M$55.20M$39.81M$43.43M$17.99M$24.42M$13.58M$6.72M$4.73M
Total equity incl. NCI$139.07M$21.73M$169.76M$264.26M$284.15M$166.53M$281.02M$246.26M$144.79M-$32.70M
Temporary (mezzanine) equity$130.96M$142.82MUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable$40.00M
Inventory$25.75M$18.74M$8.62M$2.92M$111.00KUnavailableUnavailableUnavailableUnavailableUnavailable
Accounts receivable$26.08M$18.51M$14.87M$6.22M$1.02MUnavailableUnavailableUnavailableUnavailableUnavailable
GoodwillUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Long-term debt$100.89M$108.27M$106.14MUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Accounts payable$13.95M$12.33M$4.88M$4.80M$5.74M$4.90M$10.42M$7.64M$2.43M$1.90M

Cash flow

RHYTHM PHARMACEUTICALS, INC. cash flow by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Operating cash flow-$115.68M-$113.88M-$136.16M-$173.43M-$146.00M-$121.98M-$122.75M-$62.06M-$29.46M-$23.22M
Capital expenditures$953.00K$0$47.00K$281.00K$434.00K$214.00K$3.38M$722.00K$133.00K$1.06M
Investing cash flow-$137.15M-$48.17M-$5.66M$28.03M-$62.16M$158.53M-$27.97M-$87.15M-$110.04M-$5.11M
Financing cash flow$217.96M$191.24M$74.37M$213.83M$166.48M$2.01M$163.47M$164.69M$167.20MUnavailable
Net change in cash-$34.78M$29.19M-$67.60M$68.43M-$41.68M$38.56M$12.75M$15.48M$27.70M-$28.33M
Stock-based compensation$66.82M$39.68M$32.55M$19.83M$20.80M$17.46M$11.88M$6.39M$2.28M$1.17M
Common dividends paidUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Common share repurchasesUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Depreciation & amortization$500.00K$700.00K$900.00K$896.00K$816.00K$690.00K$834.00K$442.00K$223.00K$144.00K

Derived

RHYTHM PHARMACEUTICALS, INC. derived by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Free cash flow-$116.63M-$113.88M-$136.20M-$173.71M-$146.44M-$122.19M-$126.14M-$62.78M-$29.59M-$24.28M
Gross margin89.7%89.7%88.0%91.0%81.0%UnavailableUnavailableUnavailableUnavailableUnavailable
Operating margin-101.2%-204.0%-238.1%-757.9%-5391.9%UnavailableUnavailableUnavailableUnavailableUnavailable
FCF margin-61.5%-87.5%-175.9%-734.9%-4642.9%UnavailableUnavailableUnavailableUnavailableUnavailable
SBC / revenue35.2%30.5%42.0%83.9%659.6%UnavailableUnavailableUnavailableUnavailableUnavailable
Current ratio4.41x3.24x5.58x8.90x7.10x10.10x12.38x19.05x22.42x2.36x
Revenue YoY growth45.8%68.1%227.6%649.5%UnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Net margin-103.6%-200.3%-238.5%-766.2%-2207.1%UnavailableUnavailableUnavailableUnavailableUnavailable
R&D / revenue88.2%182.9%174.3%459.6%3301.5%UnavailableUnavailableUnavailableUnavailableUnavailable
CapEx / revenue0.5%0.0%0.1%1.2%13.8%UnavailableUnavailableUnavailableUnavailableUnavailable
Long-term debt / equity0.73xUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Effective tax rateUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable

Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open RYTM in the interactive workspace to inspect any figure back to its filing.

Source filings

10-Q · Filed 2026-08-04View SEC filing
10-Q · Filed 2026-05-05View SEC filing
10-K · Filed 2026-02-26View SEC filing
10-Q · Filed 2025-11-04View SEC filing
10-Q · Filed 2025-08-05View SEC filing
10-Q · Filed 2025-05-07View SEC filing

Companies in the same industry

Every accounting identity this site checks — the balance sheet, the gross profit bridge and the cash flow statement — reconciles in every period shown.