gross profit bridgeinconsistent2023-12-31
Withheld: gross profit could not be reconciled with the rest of this filer’s statement.
Revenue
$267.95M
Fiscal year ended 2026-06-30Operating income
-$102.29M
Fiscal year ended 2026-06-30Free cash flow
$549.45M
Fiscal year ended 2026-06-30Valuation, from the filing
| Public float | $5.28B | Market value of stock held by non-affiliates, as stated on the cover page for 2025-06-30 |
|---|---|---|
| Float per share | $31.94 | Float divided by shares outstanding in the same filing. A floor under the share price on that date, not the price itself. |
| Float / revenue | 5.6× | A lower bound on the multiple, because affiliate holdings are excluded. |
| Float / equity | 10.8× | A lower bound on the multiple, because affiliate holdings are excluded. |
Every figure here is drawn from the 10-K cover page and the statements behind it, so each one traces to a filing. Public float counts only stock held by non-affiliates, which makes these floors rather than estimates: a high multiple is conclusive, a low one may mean cheap or may mean closely held. The float was measured on 2025-06-30, not today, and each multiple below it uses the figures for the fiscal year ending 2025-12-31 — the year that filing covered.
Valuation over time
26.9× earnings today, against a median of 26.9× across 3 years on record. In line with its own history.
| Float measured | Public float | Float / net income | |
|---|---|---|---|
| 2019-06-30 | $7.48B | 26.9× | |
| 2018-06-30 | $4.81B | 17.6× | |
| 2017-06-30 | $5.16B | 14909.3× |
Each float is paired with the fiscal year the filing that stated it covers. Only years where the company reported positive net income appear, because a multiple against a loss is not a multiple.
How this compares in its industry
Percentile among the Pharmaceutical Preparations filers on this site, highest value first. A high percentile means a large figure, which is good for a margin and not for leverage — the ranking says where the company sits, not whether that is where it should be.
| Measure | Reported | Percentile | |
|---|---|---|---|
| Gross margin | 98.3% | 94th | |
| Revenue YoY growth | 33.8% | 70th | |
| CapEx / revenue | 5.5% | 69th | |
| Operating margin | -40.4% | 66th | |
| Net margin | -40.4% | 61th | |
| SBC / revenue | 14.2% | 41th | |
| FCF margin | -33.9% | 58th | |
| R&D / revenue | 97.0% | 42th | |
| Current ratio | 3.83x | 50th |
IONIS PHARMACEUTICALS INC (IONS) reported revenue of $267.95M and net income of -$114.65M for the fiscal year ended 2026-06-30. This page shows 10 annual periods of income statement, balance sheet and cash flow figures normalized from IONIS PHARMACEUTICALS INC’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Pharmaceutical Preparations.
Income
| Metric | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $267.95M | $246.09M | $203.33M | $156.72M | $452.05M | $131.61M | $226.58M | $133.81M | $225.25M | $119.50M |
| Cost of revenue | $2.74M | $2.98M | $7.96M | $2.34M | $4.15M | $1.46M | $3.83M | $1.07M | $4.16M | $2.15M |
| Gross profit | $265.21M | $243.11M | $195.37M | $154.38M | $447.90M | $130.15M | $222.75M | $132.74M | $221.09M | $117.35M |
| Operating income | -$102.29M | -$117.42M | -$214.46M | -$160.18M | $139.82M | -$146.86M | -$110.82M | -$148.66M | -$66.09M | -$149.51M |
| Net income | -$114.65M | -$92.53M | -$229.39M | -$128.61M | $123.55M | -$146.94M | -$104.35M | -$140.48M | -$66.26M | -$142.80M |
| Research & development | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Weighted-average diluted shares | shares 165.42M | shares 164.87M | Unavailable | shares 159.76M | shares 182.33M | shares 158.74M | Unavailable | shares 148.59M | shares 145.96M | shares 145.54M |
| Pretax income | -$113.38M | -$92.31M | -$227.92M | -$128.39M | $123.53M | -$146.82M | -$107.04M | -$144.10M | -$66.20M | -$142.73M |
| Income tax expense | $1.26M | $218.00K | $1.48M | $213.00K | -$20.00K | $116.00K | -$2.69M | -$3.62M | $64.00K | $75.00K |
| Diluted EPS | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.70 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 |
| Selling, general & administrative | $150.40M | $150.36M | $130.19M | $96.81M | $90.62M | $76.25M | $88.08M | $61.64M | $65.11M | $52.64M |
| General & administrative | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Selling & marketing | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
Balance
| Metric | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & equivalents | $350.06M | $173.38M | $372.26M | $338.34M | $297.30M | $264.19M | $242.08M | $334.60M | $293.99M | $348.89M |
| Total assets | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B |
| Current assets | $2.49B | $2.94B | $2.99B | $2.52B | $2.58B | $2.42B | $2.62B | $2.71B | $2.33B | $2.42B |
| Total liabilities | $2.55B | $2.96B | $3.03B | $2.42B | $2.35B | $2.34B | $2.42B | $2.42B | $2.43B | $2.47B |
| Current liabilities | $315.64M | $716.59M | $781.57M | $903.46M | $897.24M | $250.29M | $309.32M | $304.57M | $306.16M | $327.65M |
| Total equity incl. NCI | $439.74M | $491.41M | $489.09M | $617.97M | $631.72M | $475.73M | $588.35M | $662.47M | $263.70M | $296.52M |
| Temporary (mezzanine) equity | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Inventory | $50.83M | $5.56M | $10.05M | $10.47M | $8.48M | $11.50M | $12.51M | $28.45M | $28.72M | $30.26M |
| Accounts receivable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Goodwill | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Long-term debt | Unavailable | Unavailable | $1.33B | Unavailable | Unavailable | Unavailable | $1.20B | Unavailable | Unavailable | Unavailable |
| Accounts payable | $47.70M | $26.03M | $28.08M | $14.33M | $22.80M | $17.46M | $42.96M | $9.05M | $9.24M | $13.08M |
Cash flow
| Metric | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | $565.53M | -$792.82M | -$137.71M | -$131.44M | $151.34M | -$150.78M | -$116.14M | -$114.99M | -$119.88M | -$149.94M |
| Capital expenditures | $16.08M | $21.76M | $21.29M | $5.27M | $12.30M | $12.58M | $25.50M | $9.06M | $6.23M | $4.49M |
| Investing cash flow | $23.50M | $536.82M | -$419.50M | $91.34M | -$120.07M | $170.46M | $68.21M | -$340.80M | $62.45M | $76.10M |
| Financing cash flow | -$412.29M | $57.26M | $591.18M | $81.22M | $1.25M | $2.20M | -$44.12M | $496.05M | $2.56M | $23.57M |
| Net change in cash | $176.68M | -$198.88M | $33.92M | $41.04M | $33.11M | $22.12M | -$92.53M | $40.61M | -$54.90M | -$50.38M |
| Stock-based compensation | $45.60M | $43.28M | $43.32M | $31.15M | $29.69M | $29.72M | $36.15M | $31.98M | $30.73M | $31.34M |
| Common dividends paid | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Common share repurchases | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Depreciation & amortization | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
Derived
| Metric | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Free cash flow | $549.45M | -$814.58M | -$159.00M | -$136.71M | $139.03M | -$163.35M | -$141.64M | -$124.05M | -$126.11M | -$154.43M |
| Gross margin | 99.0% | 98.8% | 96.1% | 98.5% | 99.1% | 98.9% | 98.3% | 99.2% | 98.2% | 98.2% |
| Operating margin | -38.2% | -47.7% | -105.5% | -102.2% | 30.9% | -111.6% | -48.9% | -111.1% | -29.3% | -125.1% |
| FCF margin | 205.1% | -331.0% | -78.2% | -87.2% | 30.8% | -124.1% | -62.5% | -92.7% | -56.0% | -129.2% |
| SBC / revenue | 17.0% | 17.6% | 21.3% | 19.9% | 6.6% | 22.6% | 16.0% | 23.9% | 13.6% | 26.2% |
| Current ratio | 7.89x | 4.10x | 3.83x | 2.79x | 2.87x | 9.66x | 8.47x | 8.91x | 7.61x | 7.37x |
| Revenue YoY growth | -40.7% | 87.0% | -10.3% | 17.1% | 100.7% | 10.1% | -30.2% | -7.2% | 19.6% | -8.4% |
| Net margin | -42.8% | -37.6% | -112.8% | -82.1% | 27.3% | -111.6% | -46.1% | -105.0% | -29.4% | -119.5% |
| R&D / revenue | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| CapEx / revenue | 6.0% | 8.8% | 10.5% | 3.4% | 2.7% | 9.6% | 11.3% | 6.8% | 2.8% | 3.8% |
| Long-term debt / equity | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Effective tax rate | Unavailable | Unavailable | Unavailable | Unavailable | -0.0% | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open IONS in the interactive workspace to inspect any figure back to its filing.
Source filings
10-Q · Filed 2026-07-29View SEC filing
10-Q · Filed 2026-04-29View SEC filing
10-K · Filed 2026-02-26View SEC filing
10-Q · Filed 2025-10-29View SEC filing
10-Q · Filed 2025-07-30View SEC filing
10-Q · Filed 2025-04-30View SEC filing
Reconciliation checks needing review
2 periods on this page do not reconcile under this site’s normalization. Read that as a limitation here before an observation about the company: the figures are the filer’s own, the filings linked above are authoritative, and a difference usually means the concepts this site selected do not match how this filer presents its statements. Nothing is adjusted to make a check pass.
gross profit bridgeinconsistent2022-12-31
Withheld: gross profit could not be reconciled with the rest of this filer’s statement.