SequelSEC

ALNYLAM PHARMACEUTICALS, INC. ALNY

Pharmaceutical Preparations · CIK 0001178670 · Fiscal year ends 1231

Revenue
$3.71B
Fiscal year ended 2025-12-31
Operating income
$501.58M
Fiscal year ended 2025-12-31
Free cash flow
$465.38M
Fiscal year ended 2025-12-31

Valuation, from the filing

Public float$42.63BMarket value of stock held by non-affiliates, as stated on the cover page for 2025-06-30
Float per share$321.44Float divided by shares outstanding in the same filing. A floor under the share price on that date, not the price itself.
Float / net income135.9×A lower bound on the multiple, because affiliate holdings are excluded.
Float / revenue11.5×A lower bound on the multiple, because affiliate holdings are excluded.
Float / equity54.0×A lower bound on the multiple, because affiliate holdings are excluded.

Every figure here is drawn from the 10-K cover page and the statements behind it, so each one traces to a filing. Public float counts only stock held by non-affiliates, which makes these floors rather than estimates: a high multiple is conclusive, a low one may mean cheap or may mean closely held. The float was measured on 2025-06-30, not today, and each multiple below it uses the figures for the fiscal year ending 2025-12-31 — the year that filing covered.

How this compares in its industry

Percentile among the Pharmaceutical Preparations filers on this site, highest value first. A high percentile means a large figure, which is good for a margin and not for leverage — the ranking says where the company sits, not whether that is where it should be.

MeasureReportedPercentile
Operating margin13.5%89th
Net margin8.4%83th
FCF margin12.5%81th
Revenue YoY growth65.2%78th
Effective tax rate2.9%29th
Gross margin81.8%70th
R&D / revenue35.5%31th
SBC / revenue9.4%33th
Current ratio2.76x39th
CapEx / revenue1.6%47th

ALNYLAM PHARMACEUTICALS, INC. (ALNY) reported revenue of $3.71B and net income of $313.75M for the fiscal year ended 2025-12-31. This page shows 10 annual periods of income statement, balance sheet and cash flow figures normalized from ALNYLAM PHARMACEUTICALS, INC.’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Pharmaceutical Preparations.

Income

ALNYLAM PHARMACEUTICALS, INC. income by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Revenue$3.71B$2.25B$1.83B$1.04B$844.29M$492.85M$219.75M$74.91M$89.91M$47.16M
Cost of revenue$677.17M$306.51M$268.22M$140.17M$115.00M$74.18M$25.06M$1.80M$0Unavailable
Gross profit$3.04B$1.94B$1.56B$897.24M$729.28M$418.67M$194.69M$73.11M$89.91MUnavailable
Operating income$501.58M-$176.88M-$282.18M-$785.07M-$708.65M-$828.44M-$939.43M-$814.67M-$500.09M-$424.59M
Net income$313.75M-$278.16M-$440.24M-$1.13B-$852.82M-$858.28M-$886.12M-$761.50M-$490.87M-$410.11M
Research & development$1.32B$1.13B$1.00B$883.02M$792.16M$654.82M$655.11M$505.42M$390.64M$382.39M
Weighted-average diluted sharesshares 134.68Mshares 127.65Mshares 124.91Mshares 121.69Mshares 118.45Mshares 114.99Mshares 109.26MUnavailableUnavailableUnavailable
Pretax income$323.15M-$377.38M-$433.52M-$1.13B-$852.14M-$855.60M-$885.25M-$760.67M-$490.87M-$410.11M
Income tax expense$9.40M-$99.22M$6.72M$4.16M$680.00K$2.68M$863.00K$823.00K$0$0
Diluted EPS$2.33$-2.18$-3.52$-9.30$-7.20$-7.46$-8.11UnavailableUnavailableUnavailable
Selling, general & administrative$1.21B$975.53M$795.65M$770.66M$620.64M$588.42M$479.00M$382.36M$199.36M$89.35M
General & administrativeUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable$199.36M$89.35M
Selling & marketingUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable

Balance

ALNYLAM PHARMACEUTICALS, INC. balance by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Cash & equivalents$1.66B$966.43M$812.69M$866.39M$819.98M$496.58M$547.18M$420.15M$645.36M$193.62M
Total assets$4.97B$4.24B$3.83B$3.55B$3.64B$3.41B$2.40B$1.57B$1.99B$1.26B
Current assets$4.05B$3.30B$2.98B$2.69B$2.81B$2.61B$1.72B$1.20B$1.76B$671.88M
Total liabilities$4.18B$4.17B$4.05B$3.70B$3.06B$2.39B$956.44M$272.84M$228.30M$342.59M
Current liabilities$1.47B$1.19B$967.79M$767.92M$695.71M$585.27M$352.59M$179.49M$144.25M$131.70M
Total equity incl. NCI$789.18M$67.09M-$220.64M-$158.22M$588.20M$1.02B$1.44B$1.30B$1.77B$920.22M
Temporary (mezzanine) equityUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Inventory$82.72M$78.51M$89.15M$128.96M$86.36M$75.20M$56.35M$24.07MUnavailableUnavailable
Accounts receivable$777.57M$405.31M$327.79M$237.96M$198.57M$102.41M$43.01M$18.76M$34.00M$23.33M
GoodwillUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Long-term debtUnavailableUnavailableUnavailableUnavailable$675.70M$191.28MUnavailableUnavailableUnavailableUnavailable
Accounts payable$115.72M$88.42M$55.52M$98.09M$73.43M$51.97M$49.88M$59.71M$28.36M$54.46M

Cash flow

ALNYLAM PHARMACEUTICALS, INC. cash flow by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Operating cash flow$524.08M-$8.31M$104.16M-$541.27M-$641.69M-$614.96M-$278.43M-$562.62M-$382.79M-$307.70M
Capital expenditures$58.70M$34.28M$62.21M$72.06M$76.37M$70.36M$140.16M$126.89M$104.21M$64.56M
Investing cash flow$436.33M-$116.84M-$336.35M$169.35M-$273.30M-$435.52M-$417.68M$272.94M-$290.36M$142.59M
Financing cash flow-$305.19M$294.16M$172.13M$425.75M$1.25B$994.98M$823.18M$65.47M$1.12B$177.83M
Net change in cash$690.16M$153.77M-$53.67M$46.40M$323.11M-$50.58M$127.00M-$224.20M$451.74M$12.72M
Stock-based compensation$348.24M$272.08M$221.68M$230.65M$165.72M$139.87M$174.84M$157.75M$92.82M$75.53M
Common dividends paidUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Common share repurchasesUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Depreciation & amortization$55.66M$56.67M$54.05M$44.47M$47.57M$34.77M$17.18M$15.25M$11.90M$15.13M

Derived

ALNYLAM PHARMACEUTICALS, INC. derived by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Free cash flow$465.38M-$42.59M$41.94M-$613.33M-$718.06M-$685.32M-$418.58M-$689.50M-$487.00M-$372.26M
Gross margin81.8%86.4%85.3%86.5%86.4%84.9%88.6%97.6%100.0%Unavailable
Operating margin13.5%-7.9%-15.4%-75.7%-83.9%-168.1%-427.5%-1087.6%-556.2%-900.3%
FCF margin12.5%-1.9%2.3%-59.1%-85.0%-139.1%-190.5%-920.5%-541.6%-789.4%
SBC / revenue9.4%12.1%12.1%22.2%19.6%28.4%79.6%210.6%103.2%160.2%
Current ratio2.76x2.78x3.08x3.51x4.04x4.47x4.87x6.69x12.23x5.10x
Revenue YoY growth65.2%23.0%76.2%22.9%71.3%124.3%193.4%-16.7%90.7%Unavailable
Net margin8.4%-12.4%-24.1%-109.0%-101.0%-174.1%-403.2%-1016.6%-545.9%-869.6%
R&D / revenue35.5%50.1%54.9%85.1%93.8%132.9%298.1%674.7%434.5%810.9%
CapEx / revenue1.6%1.5%3.4%6.9%9.0%14.3%63.8%169.4%115.9%136.9%
Long-term debt / equityUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Effective tax rate2.9%UnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable

Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open ALNY in the interactive workspace to inspect any figure back to its filing.

Source filings

10-Q · Filed 2026-10-29View SEC filing
10-Q · Filed 2026-07-30View SEC filing
10-K · Filed 2026-02-12View SEC filing
10-Q · Filed 2025-10-30View SEC filing
10-Q · Filed 2025-07-31View SEC filing
10-Q · Filed 2025-05-01View SEC filing

Companies in the same industry

Every accounting identity this site checks — the balance sheet, the gross profit bridge and the cash flow statement — reconciles in every period shown.