SequelSEC

ALNYLAM PHARMACEUTICALS, INC. ALNY

Pharmaceutical Preparations · CIK 0001178670 · Fiscal year ends 1231

Revenue
$3.71B
Fiscal year ended 2025-12-31
Operating income
$501.58M
Fiscal year ended 2025-12-31
Free cash flow
$465.38M
Fiscal year ended 2025-12-31

ALNYLAM PHARMACEUTICALS, INC. (ALNY) reported revenue of $3.71B and net income of $313.75M for the fiscal year ended 2025-12-31. This page shows 10 annual periods of income statement, balance sheet and cash flow figures normalized from ALNYLAM PHARMACEUTICALS, INC.’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Pharmaceutical Preparations.

Income

ALNYLAM PHARMACEUTICALS, INC. income by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Revenue$3.71B$2.25B$1.83B$1.04B$844.29M$492.85M$219.75M$74.91M$89.91M$47.16M
Cost of revenue$677.17M$306.51M$268.22M$140.17M$115.00M$74.18M$25.06M$1.80M$0Unavailable
Gross profit$3.04B$1.94B$1.56B$897.24M$729.28M$418.67M$194.69M$73.11M$89.91MUnavailable
Operating income$501.58M-$176.88M-$282.18M-$785.07M-$708.65M-$828.44M-$939.43M-$814.67M-$500.09M-$424.59M
Net income$313.75M-$278.16M-$440.24M-$1.13B-$852.82M-$858.28M-$886.12M-$761.50M-$490.87M-$410.11M
Research & development$1.32B$1.13B$1.00B$883.02M$792.16M$654.82M$655.11M$505.42M$390.64M$382.39M
Weighted-average diluted sharesshares 134.68Mshares 127.65Mshares 124.91Mshares 121.69Mshares 118.45Mshares 114.99Mshares 109.26MUnavailableUnavailableUnavailable
Pretax income$323.15M-$377.38M-$433.52M-$1.13B-$852.14M-$855.60M-$885.25M-$760.67M-$490.87M-$410.11M
Income tax expense$9.40M-$99.22M$6.72M$4.16M$680.00K$2.68M$863.00K$823.00K$0$0
Diluted EPS$2.33$-2.18$-3.52$-9.30$-7.20$-7.46$-8.11UnavailableUnavailableUnavailable
Selling, general & administrative$1.21B$975.53M$795.65M$770.66M$620.64M$588.42M$479.00M$382.36M$199.36M$89.35M
General & administrativeUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable$199.36M$89.35M
Selling & marketingUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable

Balance

ALNYLAM PHARMACEUTICALS, INC. balance by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Cash & equivalents$1.66B$966.43M$812.69M$866.39M$819.98M$496.58M$547.18M$420.15M$645.36M$193.62M
Total assets$4.97B$4.24B$3.83B$3.55B$3.64B$3.41B$2.40B$1.57B$1.99B$1.26B
Current assets$4.05B$3.30B$2.98B$2.69B$2.81B$2.61B$1.72B$1.20B$1.76B$671.88M
Total liabilities$4.18B$4.17B$4.05B$3.70B$3.06B$2.39B$956.44M$272.84M$228.30M$342.59M
Current liabilities$1.47B$1.19B$967.79M$767.92M$695.71M$585.27M$352.59M$179.49M$144.25M$131.70M
Total equity incl. NCI$789.18M$67.09M-$220.64M-$158.22M$588.20M$1.02B$1.44B$1.30B$1.77B$920.22M
Temporary (mezzanine) equityUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Inventory$82.72M$78.51M$89.15M$128.96M$86.36M$75.20M$56.35M$24.07MUnavailableUnavailable
Accounts receivable$777.57M$405.31M$327.79M$237.96M$198.57M$102.41M$43.01M$18.76M$34.00M$23.33M
GoodwillUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Long-term debtUnavailableUnavailableUnavailableUnavailable$675.70M$191.28MUnavailableUnavailableUnavailableUnavailable
Accounts payable$115.72M$88.42M$55.52M$98.09M$73.43M$51.97M$49.88M$59.71M$28.36M$54.46M

Cash flow

ALNYLAM PHARMACEUTICALS, INC. cash flow by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Operating cash flow$524.08M-$8.31M$104.16M-$541.27M-$641.69M-$614.96M-$278.43M-$562.62M-$382.79M-$307.70M
Capital expenditures$58.70M$34.28M$62.21M$72.06M$76.37M$70.36M$140.16M$126.89M$104.21M$64.56M
Investing cash flow$436.33M-$116.84M-$336.35M$169.35M-$273.30M-$435.52M-$417.68M$272.94M-$290.36M$142.59M
Financing cash flow-$305.19M$294.16M$172.13M$425.75M$1.25B$994.98M$823.18M$65.47M$1.12B$177.83M
Net change in cash$690.16M$153.77M-$53.67M$46.40M$323.11M-$50.58M$127.00M-$224.20M$451.74M$12.72M
Stock-based compensation$348.24M$272.08M$221.68M$230.65M$165.72M$139.87M$174.84M$157.75M$92.82M$75.53M
Common dividends paidUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Common share repurchasesUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Depreciation & amortization$55.66M$56.67M$54.05M$44.47M$47.57M$34.77M$17.18M$15.25M$11.90M$15.13M

Derived

ALNYLAM PHARMACEUTICALS, INC. derived by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-312017-12-312016-12-31
Free cash flow$465.38M-$42.59M$41.94M-$613.33M-$718.06M-$685.32M-$418.58M-$689.50M-$487.00M-$372.26M
Gross margin81.8%86.4%85.3%86.5%86.4%84.9%88.6%97.6%100.0%Unavailable
Operating margin13.5%-7.9%-15.4%-75.7%-83.9%-168.1%-427.5%-1087.6%-556.2%-900.3%
FCF margin12.5%-1.9%2.3%-59.1%-85.0%-139.1%-190.5%-920.5%-541.6%-789.4%
SBC / revenue9.4%12.1%12.1%22.2%19.6%28.4%79.6%210.6%103.2%160.2%
Current ratio2.76x2.78x3.08x3.51x4.04x4.47x4.87x6.69x12.23x5.10x
Revenue YoY growth65.2%23.0%76.2%22.9%71.3%124.3%193.4%-16.7%90.7%Unavailable
Net margin8.4%-12.4%-24.1%-109.0%-101.0%-174.1%-403.2%-1016.6%-545.9%-869.6%
R&D / revenue35.5%50.1%54.9%85.1%93.8%132.9%298.1%674.7%434.5%810.9%
CapEx / revenue1.6%1.5%3.4%6.9%9.0%14.3%63.8%169.4%115.9%136.9%
Long-term debt / equityUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable
Effective tax rate2.9%UnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailableUnavailable

Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open ALNY in the interactive workspace to inspect any figure back to its filing.

Source filings

10-Q · Filed 2026-07-30View SEC filing
10-K · Filed 2026-02-12View SEC filing
10-Q · Filed 2025-10-30View SEC filing
10-Q · Filed 2025-07-31View SEC filing
10-Q · Filed 2025-05-01View SEC filing
10-K · Filed 2025-02-13View SEC filing

Companies in the same industry

Every accounting identity this site checks — the balance sheet, the gross profit bridge and the cash flow statement — reconciles in every period shown.