Revenue
$54.03M
Fiscal year ended 2025-12-31Operating income
-$472.13M
Fiscal year ended 2025-12-31Free cash flow
-$377.29M
Fiscal year ended 2025-12-31Valuation, from the filing
| Public float | $1.91B | Market value of stock held by non-affiliates, as stated on the cover page for 2025-06-30 |
|---|---|---|
| Float per share | $32.67 | Float divided by shares outstanding in the same filing. A floor under the share price on that date, not the price itself. |
| Float / revenue | 35.4× | A lower bound on the multiple, because affiliate holdings are excluded. |
| Float / equity | 1.6× | A lower bound on the multiple, because affiliate holdings are excluded. |
Every figure here is drawn from the 10-K cover page and the statements behind it, so each one traces to a filing. Public float counts only stock held by non-affiliates, which makes these floors rather than estimates: a high multiple is conclusive, a low one may mean cheap or may mean closely held. The float was measured on 2025-06-30, not today, and each multiple below it uses the figures for the fiscal year ending 2025-12-31 — the year that filing covered.
How this compares in its industry
Percentile among the Pharmaceutical Preparations filers on this site, highest value first. A high percentile means a large figure, which is good for a margin and not for leverage — the ranking says where the company sits, not whether that is where it should be.
| Measure | Reported | Percentile | |
|---|---|---|---|
| Current ratio | 11.46x | 83th | |
| Gross margin | 88.3% | 80th | |
| Revenue YoY growth | 48.0% | 75th | |
| CapEx / revenue | 8.0% | 73th | |
| FCF margin | -698.3% | 28th | |
| R&D / revenue | 628.4% | 69th | |
| SBC / revenue | 97.3% | 67th | |
| Net margin | -764.0% | 35th | |
| Operating margin | -873.9% | 35th |
AGIOS PHARMACEUTICALS, INC. (AGIO) reported revenue of $54.03M and net income of -$412.78M for the fiscal year ended 2025-12-31. This page shows 10 annual periods of income statement, balance sheet and cash flow figures normalized from AGIOS PHARMACEUTICALS, INC.’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Pharmaceutical Preparations.
Income
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $54.03M | $36.50M | $26.82M | $14.24M | $0 | $0 | $117.91M | $94.39M | $43.01M | $69.89M |
| Cost of revenue | $6.34M | $4.16M | $2.88M | $1.70M | $0 | $0 | $1.32M | $1.40M | $0 | $0 |
| Gross profit | $47.68M | $32.33M | $23.94M | $12.54M | $0 | $0 | $116.60M | $92.99M | $43.01M | $69.89M |
| Operating income | -$472.13M | -$425.74M | -$391.49M | -$389.05M | -$378.42M | -$335.92M | -$316.27M | -$362.48M | -$320.79M | -$200.98M |
| Net income | -$412.78M | $673.72M | -$352.09M | -$231.80M | $1.60B | -$327.37M | -$411.47M | -$346.03M | -$314.67M | -$198.47M |
| Research & development | $339.54M | $301.29M | $295.53M | $279.91M | $256.97M | $220.81M | $214.26M | $341.32M | $292.68M | $220.16M |
| Weighted-average diluted shares | shares 57.97M | shares 57.89M | shares 55.65M | shares 54.79M | shares 60.45M | shares 69.00M | shares 59.99M | Unavailable | Unavailable | Unavailable |
| Pretax income | -$413.80M | $717.97M | -$352.09M | -$231.80M | -$356.51M | -$329.30M | -$301.41M | -$346.03M | -$314.67M | -$198.47M |
| Income tax expense | -$1.02M | $44.24M | $0 | $0 | Unavailable | Unavailable | $0 | $0 | $0 | $0 |
| Diluted EPS | $-7.12 | $11.64 | $-6.33 | $-4.23 | $26.55 | $-4.74 | $-6.86 | Unavailable | Unavailable | Unavailable |
| Selling, general & administrative | $180.28M | $156.78M | $119.90M | $121.67M | $121.44M | $115.10M | $102.01M | $114.14M | $71.12M | $50.71M |
| General & administrative | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | $71.12M | $50.71M |
| Selling & marketing | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
Balance
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & equivalents | $89.13M | $76.25M | $88.20M | $139.26M | $203.13M | $127.44M | $80.93M | $70.50M | $102.72M | $160.75M |
| Total assets | $1.30B | $1.66B | $937.12M | $1.24B | $1.44B | $852.95M | $890.74M | $858.46M | $614.40M | $619.09M |
| Current assets | $942.05M | $965.60M | $833.84M | $832.77M | $1.06B | $636.68M | $611.70M | $613.78M | $445.26M | $559.89M |
| Total liabilities | $104.11M | $122.24M | $126.10M | $137.90M | $145.76M | $453.45M | $250.21M | $170.92M | $238.89M | $260.50M |
| Current liabilities | $82.21M | $81.16M | $67.96M | $62.63M | $59.83M | $94.39M | $92.89M | $93.50M | $94.94M | $88.43M |
| Total equity incl. NCI | $1.19B | $1.54B | $811.02M | $1.10B | $1.29B | $399.50M | $640.53M | $687.54M | $375.50M | $358.59M |
| Temporary (mezzanine) equity | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Inventory | $32.92M | $27.62M | $19.08M | $8.49M | $0 | $14.70M | $7.33M | $869.00K | $0 | Unavailable |
| Accounts receivable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Goodwill | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Long-term debt | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Accounts payable | $18.36M | $16.64M | $9.78M | $18.62M | $16.70M | $17.72M | $21.90M | $17.88M | $22.77M | $17.11M |
Cash flow
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | -$372.98M | -$389.84M | -$296.06M | -$309.48M | -$407.32M | -$290.76M | -$370.62M | -$304.42M | -$285.23M | $38.56M |
| Capital expenditures | $4.32M | $1.68M | $999.00K | $4.88M | $5.74M | $14.11M | $12.03M | $6.99M | $4.63M | $9.92M |
| Investing cash flow | $377.18M | $363.44M | $239.58M | $243.26M | $1.25B | $75.75M | $91.44M | -$273.82M | -$57.91M | -$119.35M |
| Financing cash flow | $8.68M | $14.44M | $5.43M | $2.35M | -$765.77M | $261.52M | $289.61M | $546.02M | $285.11M | $169.78M |
| Net change in cash | $12.88M | -$11.96M | -$51.05M | -$63.87M | $75.69M | $46.50M | $10.43M | -$32.22M | -$58.03M | $88.99M |
| Stock-based compensation | $52.55M | $42.85M | $44.77M | $49.30M | $53.51M | $61.60M | $58.05M | $73.36M | $47.81M | $42.09M |
| Common dividends paid | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Common share repurchases | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Depreciation & amortization | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | $8.09M | $7.17M | $6.43M | Unavailable |
Derived
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|
| Free cash flow | -$377.29M | -$391.53M | -$297.06M | -$314.36M | -$413.06M | -$304.86M | -$382.65M | -$311.41M | -$289.86M | $28.65M |
| Gross margin | 88.3% | 88.6% | 89.3% | 88.0% | Unavailable | Unavailable | 98.9% | 98.5% | 100.0% | 100.0% |
| Operating margin | -873.9% | -1166.5% | -1459.5% | -2732.1% | Unavailable | Unavailable | Unavailable | -384.0% | -745.8% | -287.6% |
| FCF margin | -698.3% | -1072.7% | -1107.5% | -2207.6% | Unavailable | Unavailable | Unavailable | -329.9% | -673.9% | 41.0% |
| SBC / revenue | 97.3% | 117.4% | 166.9% | 346.2% | Unavailable | Unavailable | Unavailable | 77.7% | 111.2% | 60.2% |
| Current ratio | 11.46x | 11.90x | 12.27x | 13.30x | 17.79x | 6.74x | 6.59x | 6.56x | 4.69x | 6.33x |
| Revenue YoY growth | 48.0% | 36.1% | 88.4% | Unavailable | Unavailable | -100.0% | 24.9% | 119.4% | -38.5% | Unavailable |
| Net margin | -764.0% | 1845.9% | -1312.6% | -1627.8% | Unavailable | Unavailable | Unavailable | -366.6% | -731.6% | -284.0% |
| R&D / revenue | 628.4% | 825.5% | 1101.8% | 1965.7% | Unavailable | Unavailable | Unavailable | 361.6% | 680.5% | 315.0% |
| CapEx / revenue | 8.0% | 4.6% | 3.7% | 34.3% | Unavailable | Unavailable | Unavailable | 7.4% | 10.8% | 14.2% |
| Long-term debt / equity | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
| Effective tax rate | Unavailable | 6.2% | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable |
Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open AGIO in the interactive workspace to inspect any figure back to its filing.
Source filings
10-Q · Filed 2026-07-30View SEC filing
10-Q · Filed 2026-04-29View SEC filing
10-K · Filed 2026-02-12View SEC filing
10-Q · Filed 2025-10-30View SEC filing
10-Q · Filed 2025-07-31View SEC filing
10-Q · Filed 2025-05-01View SEC filing
Every accounting identity this site checks — the balance sheet, the gross profit bridge and the cash flow statement — reconciles in every period shown.