SequelSEC

Krystal Biotech, Inc. KRYS

Biological Products, (No Diagnostic Substances) · CIK 0001711279 · Fiscal year ends 1231

Revenue
$389.13M
Fiscal year ended 2025-12-31
Operating income
$161.30M
Fiscal year ended 2025-12-31
Free cash flow
$188.91M
Fiscal year ended 2025-12-31

Valuation, from the filing

Public float$3.50BMarket value of stock held by non-affiliates, as stated on the cover page for 2025-06-30
Float per share$119.73Float divided by shares outstanding in the same filing. A floor under the share price on that date, not the price itself.
Float / net income17.1×A lower bound on the multiple, because affiliate holdings are excluded.
Float / revenue9.0×A lower bound on the multiple, because affiliate holdings are excluded.
Float / equity2.9×A lower bound on the multiple, because affiliate holdings are excluded.

Every figure here is drawn from the 10-K cover page and the statements behind it, so each one traces to a filing. Public float counts only stock held by non-affiliates, which makes these floors rather than estimates: a high multiple is conclusive, a low one may mean cheap or may mean closely held. The float was measured on 2025-06-30, not today, and each multiple below it uses the figures for the fiscal year ending 2025-12-31 — the year that filing covered.

Valuation over time

17.1× earnings today, against a median of 51.6× across 3 years on record. Below its own history.

Float measuredPublic floatFloat / net income
2025-06-30$3.50B17.1×
2024-06-30$4.60B51.6×
2023-06-30$2.80B256.1×

Each float is paired with the fiscal year the filing that stated it covers. Only years where the company reported positive net income appear, because a multiple against a loss is not a multiple.

How this compares in its industry

Percentile among the Biological Products, (No Diagnostic Substances) filers on this site, highest value first. A high percentile means a large figure, which is good for a margin and not for leverage — the ranking says where the company sits, not whether that is where it should be.

MeasureReportedPercentile
Effective tax rate-8.1%0th
FCF margin48.5%100th
Operating margin41.5%100th
Net margin52.6%97th
R&D / revenue14.9%9th
Current ratio9.95x83th
SBC / revenue14.0%26th
Revenue YoY growth33.9%66th
CapEx / revenue3.1%42th

Krystal Biotech, Inc. (KRYS) reported revenue of $389.13M and net income of $204.83M for the fiscal year ended 2025-12-31. This page shows 5 annual periods of income statement, balance sheet and cash flow figures normalized from Krystal Biotech, Inc.’s SEC filings, each linked to the filing it came from. It is classified by the SEC under Biological Products, (No Diagnostic Substances).

Income

Krystal Biotech, Inc. income by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue$389.13M$290.52M$50.70M$0$0
Cost of revenueUnavailableUnavailableUnavailableUnavailableUnavailable
Gross profitUnavailableUnavailableUnavailableUnavailableUnavailable
Operating income$161.30M$65.75M-$109.62M-$145.20M-$68.28M
Net income$204.83M$89.16M$10.93M-$139.98M-$69.57M
Research & development$58.04M$53.58M$46.43M$42.46M$27.88M
Weighted-average diluted sharesshares 29.95Mshares 29.74Mshares 27.75Mshares 25.49Mshares 22.20M
Pretax income$189.47M$95.36M$12.90M-$139.98M-$69.57M
Income tax expense-$15.36M$6.20M$1.96M$0$0
Diluted EPS$6.84$3.00$0.39$-5.49$-3.13
Selling, general & administrative$146.74M$113.63M$98.29M$77.74MUnavailable
General & administrativeUnavailableUnavailable$98.40M$77.74M$40.39M
Selling & marketingUnavailableUnavailableUnavailableUnavailableUnavailable

Balance

Krystal Biotech, Inc. balance by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-31
Cash & equivalents$496.30M$344.86M$358.33M$161.90M$341.25M
Total assets$1.33B$1.06B$818.36M$558.45M$626.30M
Current assets$1.02B$742.04M$587.91M$383.78M$442.27M
Total liabilities$114.23M$109.46M$39.71M$36.22M$32.72M
Current liabilities$102.94M$102.00M$33.09M$28.85M$25.74M
Total equity incl. NCI$1.22B$946.38M$778.64M$522.23M$593.58M
Temporary (mezzanine) equityUnavailableUnavailableUnavailableUnavailableUnavailable
Inventory$40.48M$26.51M$6.98M$0Unavailable
Accounts receivable$127.42M$104.75M$42.04M$0Unavailable
GoodwillUnavailableUnavailableUnavailableUnavailableUnavailable
Long-term debtUnavailableUnavailableUnavailableUnavailableUnavailable
Accounts payable$3.24M$4.98M$4.13M$3.98M$8.40M

Cash flow

Krystal Biotech, Inc. cash flow by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-31
Operating cash flow$200.86M$123.42M-$88.80M-$100.57M-$47.94M
Capital expenditures$11.95M$4.24M$11.80M$52.98M$68.34M
Investing cash flow-$58.42M-$163.44M$82.64M-$114.08M-$226.77M
Financing cash flow$8.70M$27.01M$202.75M$35.35M$347.68M
Net change in cash$151.44M-$13.46M$196.43M-$179.35M$72.98M
Stock-based compensation$54.51M$49.13M$39.93M$33.23M$15.32M
Common dividends paidUnavailableUnavailableUnavailableUnavailableUnavailable
Common share repurchasesUnavailableUnavailableUnavailableUnavailableUnavailable
Depreciation & amortizationUnavailableUnavailableUnavailable$4.06M$2.77M

Derived

Krystal Biotech, Inc. derived by fiscal year, in US dollars, normalized from SEC filings.
Metric2025-12-312024-12-312023-12-312022-12-312021-12-31
Free cash flow$188.91M$119.18M-$100.60M-$153.55M-$116.27M
Gross marginUnavailableUnavailableUnavailableUnavailableUnavailable
Operating margin41.5%22.6%-216.2%UnavailableUnavailable
FCF margin48.5%41.0%-198.4%UnavailableUnavailable
SBC / revenue14.0%16.9%78.8%UnavailableUnavailable
Current ratio9.95x7.28x17.76x13.30x17.18x
Revenue YoY growth33.9%473.0%UnavailableUnavailableUnavailable
Net margin52.6%30.7%21.6%UnavailableUnavailable
R&D / revenue14.9%18.4%91.6%UnavailableUnavailable
CapEx / revenue3.1%1.5%23.3%UnavailableUnavailable
Long-term debt / equityUnavailableUnavailableUnavailableUnavailableUnavailable
Effective tax rate-8.1%6.5%15.2%UnavailableUnavailable

Amounts are abbreviated; the exact reported value is carried in each cell. — means unavailable, not zero. Open KRYS in the interactive workspace to inspect any figure back to its filing.

Source filings

10-Q · Filed 2026-08-03View SEC filing
10-Q · Filed 2026-05-04View SEC filing
10-K · Filed 2026-02-17View SEC filing
10-Q · Filed 2025-11-03View SEC filing
10-Q · Filed 2025-08-04View SEC filing
10-Q · Filed 2025-05-06View SEC filing

Companies in the same industry

Every accounting identity this site checks — the balance sheet, the gross profit bridge and the cash flow statement — reconciles in every period shown.